Sensitivity of BRCA2 mutated human cell lines to Aurora kinase inhibition. [electronic resource]
Producer: 20120611Description: 425-34 p. digitalISSN:- 1573-0646
- Antineoplastic Agents -- pharmacology
- Aurora Kinases
- BRCA2 Protein -- genetics
- Benzamides -- pharmacology
- Breast Neoplasms -- enzymology
- Cell Death -- drug effects
- Cell Line, Tumor
- Cell Size -- drug effects
- Cell Survival -- drug effects
- Cytokinesis -- drug effects
- Dose-Response Relationship, Drug
- Female
- Humans
- Inhibitory Concentration 50
- Mitosis -- drug effects
- Molecular Targeted Therapy
- Mutation
- Pancreatic Neoplasms -- enzymology
- Ploidies
- Protein Kinase Inhibitors -- pharmacology
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Quinazolines -- pharmacology
- RNA, Messenger -- metabolism
- Transfection
- Tumor Suppressor Protein p53 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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