PKB/Akt promotes DSB repair in cancer cells through upregulating Mre11 expression following ionizing radiation. [electronic resource]
Producer: 20110413Description: 944-55 p. digitalISSN:- 1476-5594
- DNA Breaks, Double-Stranded -- radiation effects
- DNA Repair -- genetics
- DNA-Binding Proteins -- biosynthesis
- Enzyme Activation -- physiology
- Gene Expression
- Gene Expression Regulation, Neoplastic -- physiology
- Gene Knockdown Techniques
- Glycogen Synthase Kinase 3 -- genetics
- Glycogen Synthase Kinase 3 beta
- HeLa Cells
- Humans
- Lymphoid Enhancer-Binding Factor 1 -- genetics
- MRE11 Homologue Protein
- Neoplasms -- genetics
- Oligonucleotide Array Sequence Analysis
- Proto-Oncogene Proteins c-akt -- metabolism
- Radiation Tolerance -- genetics
- Radiation, Ionizing
- Signal Transduction -- physiology
- Transfection
- beta Catenin -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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