In vitro degradation and antitumor activity of oxime bond-linked daunorubicin-GnRH-III bioconjugates and DNA-binding properties of daunorubicin-amino acid metabolites. [electronic resource]
Producer: 20110916Description: 469-83 p. digitalISSN:- 1438-2199
- Amino Acid Sequence
- Animals
- Antibiotics, Antineoplastic -- chemical synthesis
- Cathepsin B -- chemistry
- Cell Line, Tumor
- Cell Survival -- drug effects
- DNA -- chemistry
- Daunorubicin -- analogs & derivatives
- Fluorescence
- Gonadotropin-Releasing Hormone -- pharmacokinetics
- Humans
- Liver -- drug effects
- Lysosomes -- drug effects
- Molecular Structure
- Oximes -- pharmacokinetics
- Peptide Fragments -- chemistry
- Pyrrolidonecarboxylic Acid -- analogs & derivatives
- Rats
- Serum -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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