ERK activation by the polyphenols fisetin and resveratrol provides neuroprotection in multiple models of Huntington's disease. [electronic resource]
Producer: 20111207Description: 261-70 p. digitalISSN:- 1460-2083
- Animals
- Disease Models, Animal
- Drosophila -- drug effects
- Enzyme Activation -- drug effects
- Extracellular Signal-Regulated MAP Kinases -- genetics
- Flavonoids -- pharmacology
- Flavonols
- Gene Dosage -- drug effects
- Gene Expression Regulation -- drug effects
- Huntingtin Protein
- Huntington Disease -- enzymology
- JNK Mitogen-Activated Protein Kinases -- genetics
- Mice
- Motor Activity -- drug effects
- Nerve Tissue Proteins -- genetics
- Neuroprotective Agents -- pharmacology
- Nuclear Proteins -- genetics
- PC12 Cells
- Rats
- Resveratrol
- Stilbenes -- pharmacology
- Survival Analysis
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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