RBP-J is not required for granule neuron progenitor development and medulloblastoma initiated by Hedgehog pathway activation in the external germinal layer. [electronic resource]
Producer: 20110111Description: 27 p. digitalISSN:- 1749-8104
- Animals
- Animals, Newborn
- Basic Helix-Loop-Helix Transcription Factors -- deficiency
- Cell Differentiation -- genetics
- Cells, Cultured
- Cerebellum -- cytology
- Embryo, Nonmammalian
- Eye Proteins -- metabolism
- Gene Expression Regulation, Developmental -- genetics
- Hedgehog Proteins -- metabolism
- Homeodomain Proteins -- metabolism
- Immunoglobulin J Recombination Signal Sequence-Binding Protein -- genetics
- Medulloblastoma -- etiology
- Mice
- Mice, Transgenic
- Neural Stem Cells -- physiology
- PAX6 Transcription Factor
- Paired Box Transcription Factors -- metabolism
- Patched Receptors
- Patched-1 Receptor
- Proliferating Cell Nuclear Antigen -- metabolism
- Receptors, Cell Surface -- deficiency
- Receptors, Notch -- metabolism
- Repressor Proteins -- metabolism
- Signal Transduction -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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