G-protein coupled receptor kinase 5 mediates lipopolysaccharide-induced NFκB activation in primary macrophages and modulates inflammation in vivo in mice. [electronic resource]
Producer: 20110414Description: 1323-33 p. digitalISSN:- 1097-4652
- Animals
- Cells, Cultured
- Cytokines -- metabolism
- Female
- G-Protein-Coupled Receptor Kinase 5 -- deficiency
- I-kappa B Proteins -- metabolism
- Inflammation -- chemically induced
- Inflammation Mediators -- metabolism
- Lipopolysaccharides -- pharmacology
- Lung -- drug effects
- Macrophages, Peritoneal -- drug effects
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- NF-KappaB Inhibitor alpha
- NF-kappa B -- metabolism
- Neutrophil Infiltration -- drug effects
- Phosphorylation
- Signal Transduction -- drug effects
- Time Factors
- Toll-Like Receptor 4 -- agonists
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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