α-Tocopherol quinone inhibits β-amyloid aggregation and cytotoxicity, disaggregates preformed fibrils and decreases the production of reactive oxygen species, NO and inflammatory cytokines. [electronic resource]
Producer: 20111122Description: 914-22 p. digitalISSN:- 1872-9754
- Amyloid -- antagonists & inhibitors
- Amyloid beta-Peptides -- antagonists & inhibitors
- Animals
- Antioxidants -- pharmacology
- CHO Cells
- Cell Line, Tumor
- Cricetinae
- Cricetulus
- Cytokines -- antagonists & inhibitors
- Down-Regulation -- drug effects
- Humans
- Inflammation Mediators -- antagonists & inhibitors
- Neurons -- drug effects
- Nitric Oxide -- antagonists & inhibitors
- Reactive Oxygen Species -- antagonists & inhibitors
- Vitamin E -- analogs & derivatives
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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