Evaluation of the mTOR inhibitor, everolimus, in combination with cytotoxic antitumor agents using human tumor models in vitro and in vivo. [electronic resource]
Producer: 20110304Description: 58-78 p. digitalISSN:- 1473-5741
- Animals
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cisplatin -- administration & dosage
- Deoxycytidine -- administration & dosage
- Dose-Response Relationship, Drug
- Doxorubicin -- administration & dosage
- Drug Screening Assays, Antitumor
- Drug Synergism
- Epothilones -- administration & dosage
- Everolimus
- Female
- Fluorouracil -- administration & dosage
- HCT116 Cells
- Humans
- Mice
- Mice, Nude
- Paclitaxel -- administration & dosage
- Sirolimus -- administration & dosage
- TOR Serine-Threonine Kinases -- antagonists & inhibitors
- Xenograft Model Antitumor Assays
- Gemcitabine
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Publication Type: Journal Article
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