Baicalein significantly protects human retinal pigment epithelium cells against H₂O₂-induced oxidative stress by scavenging reactive oxygen species and downregulating the expression of matrix metalloproteinase-9 and vascular endothelial growth factor. [electronic resource]
Producer: 20110328Description: 421-9 p. digitalISSN:- 1557-7732
- Antioxidants -- metabolism
- Cell Survival -- drug effects
- Dose-Response Relationship, Drug
- Down-Regulation -- drug effects
- Flavanones -- metabolism
- Humans
- Hydrogen Peroxide -- administration & dosage
- Macular Degeneration -- drug therapy
- Matrix Metalloproteinase 9 -- analysis
- Oxidative Stress -- drug effects
- Reactive Oxygen Species -- analysis
- Retinal Pigment Epithelium -- drug effects
- Vascular Endothelial Growth Factor A -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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