Efficacy of the multi-kinase inhibitor enzastaurin is dependent on cellular signaling context. [electronic resource]
Producer: 20110310Description: 2814-24 p. digitalISSN:- 1538-8514
- Animals
- Base Sequence
- Carcinoma, Squamous Cell -- enzymology
- Cell Cycle
- Cell Line
- Cell Proliferation -- drug effects
- Cyclin D1 -- genetics
- DNA Primers
- Female
- Head and Neck Neoplasms -- enzymology
- Humans
- Indoles -- pharmacology
- Mice
- Mice, Nude
- Oligonucleotide Array Sequence Analysis
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-akt -- metabolism
- RNA, Small Interfering
- Signal Transduction -- drug effects
- Transplantation, Heterologous
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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