Design, synthesis and biological evaluation of estradiol-PEG-linked platinum(II) hybrid molecules: comparative molecular modeling study of three distinct families of hybrids. [electronic resource]
Producer: 20110331Description: 94-103 p. digitalISSN:- 1878-5867
- Antineoplastic Agents -- chemical synthesis
- Binding Sites -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- Estradiol -- chemistry
- Estrogen Receptor alpha -- chemistry
- Humans
- Models, Molecular
- Molecular Conformation
- Organometallic Compounds -- chemical synthesis
- Platinum -- chemistry
- Polyethylene Glycols -- chemistry
- Stereoisomerism
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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