The cytotoxic mechanism of malondialdehyde and protective effect of carnosine via protein cross-linking/mitochondrial dysfunction/reactive oxygen species/MAPK pathway in neurons. [electronic resource]
Producer: 20110324Description: 184-94 p. digitalISSN:- 1879-0712
- Animals
- Apoptosis -- drug effects
- Carnosine -- pharmacology
- Cells, Cultured
- Cerebral Cortex -- cytology
- Cross-Linking Reagents -- toxicity
- Dose-Response Relationship, Drug
- MAP Kinase Signaling System -- drug effects
- Malondialdehyde -- toxicity
- Membrane Potential, Mitochondrial -- drug effects
- Mitochondria -- drug effects
- Necrosis -- chemically induced
- Neurons -- cytology
- Proteins -- chemistry
- Rats
- Rats, Sprague-Dawley
- Reactive Oxygen Species -- metabolism
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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