New anthracenedione derivatives with improved biological activity by virtue of stable drug-DNA adduct formation. [electronic resource]
Producer: 20101109Description: 6851-66 p. digitalISSN:- 1520-4804
- Anthraquinones -- chemical synthesis
- Antineoplastic Agents -- chemical synthesis
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- DNA Adducts -- chemistry
- DNA-Directed RNA Polymerases -- antagonists & inhibitors
- Drug Screening Assays, Antitumor
- Escherichia coli Proteins -- antagonists & inhibitors
- Formaldehyde -- chemistry
- Humans
- Hydrogen-Ion Concentration
- Isoquinolines -- chemical synthesis
- Mitoxantrone -- analogs & derivatives
- Models, Molecular
- Prodrugs -- chemical synthesis
- Structure-Activity Relationship
- Transcription, Genetic -- drug effects
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.