Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment. [electronic resource]
Producer: 20110124Description: 3515-33 p. digitalISSN:- 1551-4005
- Animals
- Antirheumatic Agents -- pharmacology
- Apoptosis Regulatory Proteins
- Autophagy
- Breast Neoplasms -- metabolism
- Caveolin 1 -- genetics
- Cell Hypoxia
- Cell Line, Tumor
- Cell Survival
- Chloroquine -- pharmacology
- Coculture Techniques
- Female
- Fibroblasts -- metabolism
- Glutathione Synthase -- antagonists & inhibitors
- Humans
- Hypoxia-Inducible Factor 1, alpha Subunit -- metabolism
- Intracellular Signaling Peptides and Proteins -- metabolism
- Membrane Proteins -- metabolism
- Mice
- Mice, Knockout
- Microtubule-Associated Proteins -- metabolism
- NF-kappa B -- metabolism
- Oxidative Stress
- Paracrine Communication
- Phosphoric Monoester Hydrolases
- Proto-Oncogene Proteins -- metabolism
- RNA Interference
- RNA, Small Interfering -- metabolism
- Stromal Cells -- metabolism
- Tumor Microenvironment
- Tumor Suppressor Proteins -- metabolism
- Up-Regulation
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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