Carbohydrate-response-element-binding protein (ChREBP) and not the liver X receptor α (LXRα) mediates elevated hepatic lipogenic gene expression in a mouse model of glycogen storage disease type 1. [electronic resource]
Producer: 20101230Description: 249-54 p. digitalISSN:- 1470-8728
- Animals
- Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
- Cholesterol -- metabolism
- Disease Models, Animal
- Gene Expression Regulation
- Glucose-6-Phosphatase -- adverse effects
- Glycogen Storage Disease -- enzymology
- Humans
- Imidazoles -- administration & dosage
- Liver -- enzymology
- Liver Glycogen -- metabolism
- Liver X Receptors
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Nuclear Proteins -- deficiency
- Orphan Nuclear Receptors -- deficiency
- Pyridines -- administration & dosage
- RNA -- genetics
- Transcription Factors -- deficiency
- Triglycerides -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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