p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation. [electronic resource]
Producer: 20110204Description: 781-94 p. digitalISSN:- 1755-148X
- 9,10-Dimethyl-1,2-benzanthracene
- Animals
- Cell Cycle -- radiation effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Cellular Senescence -- drug effects
- Clone Cells
- Disease Models, Animal
- Disease Progression
- Humans
- Imidazoles -- pharmacology
- Melanocytes -- drug effects
- Melanoma -- metabolism
- Mice
- Mice, Inbred C57BL
- Nevus -- metabolism
- Pigmentation -- drug effects
- Piperazines -- pharmacology
- Proto-Oncogene Proteins -- metabolism
- Skin Neoplasms -- metabolism
- Staining and Labeling
- Survival Analysis
- Transcription, Genetic -- drug effects
- Tumor Suppressor Protein p53 -- genetics
- Ubiquitin-Protein Ligases -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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