Rheb activates AMPK and reduces p27Kip1 levels in Tsc2-null cells via mTORC1-independent mechanisms: implications for cell proliferation and tumorigenesis. [electronic resource]
Producer: 20110111Description: 6543-56 p. digitalISSN:- 1476-5594
- AMP-Activated Protein Kinases -- metabolism
- Animals
- Cell Line, Tumor
- Cell Proliferation
- Cell Transformation, Neoplastic -- metabolism
- Colonic Neoplasms -- metabolism
- Cyclin-Dependent Kinase 2 -- analysis
- Cyclin-Dependent Kinase Inhibitor p27 -- analysis
- Female
- Humans
- Mechanistic Target of Rapamycin Complex 1
- Mice
- Mice, Nude
- Monomeric GTP-Binding Proteins -- metabolism
- Multiprotein Complexes
- Neuropeptides -- metabolism
- Proteins -- metabolism
- Ras Homolog Enriched in Brain Protein
- TOR Serine-Threonine Kinases
- Tuberous Sclerosis Complex 2 Protein
- Tumor Suppressor Proteins -- analysis
- Up-Regulation
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
There are no comments on this title.
Log in to your account to post a comment.