2-Methoxy-4-vinylphenol can induce cell cycle arrest by blocking the hyper-phosphorylation of retinoblastoma protein in benzo[a]pyrene-treated NIH3T3 cells. [electronic resource]
Producer: 20101123Description: 752-7 p. digitalISSN:- 1090-2104
- Animals
- Benzo(a)pyrene -- toxicity
- Carcinogens, Environmental -- toxicity
- Cell Cycle -- drug effects
- Cell Proliferation -- drug effects
- Chemoprevention
- Cyclin-Dependent Kinase 2 -- metabolism
- Cyclin-Dependent Kinase 4 -- metabolism
- Cyclin-Dependent Kinase Inhibitor p15 -- metabolism
- Cyclin-Dependent Kinase Inhibitor p21 -- metabolism
- G1 Phase -- drug effects
- Guaiacol -- analogs & derivatives
- Mice
- NIH 3T3 Cells
- Phosphorylation -- drug effects
- Retinoblastoma Protein -- metabolism
- Vinyl Compounds -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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