The use of protein array to identify targetable receptor tyrosine kinases for treatment of human colon cancer. [electronic resource]
Producer: 20101223Description: 829-35 p. digitalISSN:- 1791-2423
- Aged
- Animals
- Antibodies, Monoclonal -- pharmacology
- Antibodies, Monoclonal, Humanized
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Caco-2 Cells
- Colonic Neoplasms -- drug therapy
- Enzyme Activation
- Female
- Fluorouracil -- administration & dosage
- Humans
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Middle Aged
- Mitogen-Activated Protein Kinases -- metabolism
- Molecular Targeted Therapy
- Phosphorylation
- Protein Array Analysis
- Protein Kinase Inhibitors -- administration & dosage
- Proto-Oncogene Proteins c-akt -- metabolism
- Receptor Protein-Tyrosine Kinases -- antagonists & inhibitors
- Receptor, ErbB-2 -- antagonists & inhibitors
- Time Factors
- Trastuzumab
- Tumor Burden
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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