Cocaine-induced chromatin remodeling increases brain-derived neurotrophic factor transcription in the rat medial prefrontal cortex, which alters the reinforcing efficacy of cocaine. [electronic resource]
Producer: 20100920Description: 11735-44 p. digitalISSN:- 1529-2401
- Animals
- Behavior, Addictive -- metabolism
- Brain-Derived Neurotrophic Factor -- biosynthesis
- Chromatin Assembly and Disassembly -- drug effects
- Cocaine -- administration & dosage
- Cocaine-Related Disorders -- metabolism
- Male
- Prefrontal Cortex -- drug effects
- Rats
- Rats, Sprague-Dawley
- Reinforcement, Psychology
- Self Administration
- Transcription, Genetic -- drug effects
- Up-Regulation -- drug effects
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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