PARP1 is activated at telomeres upon G4 stabilization: possible target for telomere-based therapy. [electronic resource]
Producer: 20101228Description: 6280-93 p. digitalISSN:- 1476-5594
- Acridines -- metabolism
- Animals
- Antineoplastic Agents -- metabolism
- DNA Damage
- DNA Repair -- drug effects
- Drug Synergism
- Enzyme Activation -- drug effects
- Enzyme Inhibitors -- pharmacology
- G-Quadruplexes -- drug effects
- HCT116 Cells
- HT29 Cells
- Humans
- Male
- Mice
- Poly(ADP-ribose) Polymerases -- metabolism
- Protein Transport -- drug effects
- Telomere -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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