PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice. [electronic resource]
Producer: 20100923Description: 15145-50 p. digitalISSN:- 1091-6490
- Adenomatous Polyposis Coli -- etiology
- Animals
- Base Sequence
- Cell Line, Tumor
- Cell Proliferation
- Chromosomes, Human, Pair 6 -- genetics
- Cocarcinogenesis
- Colorectal Neoplasms -- genetics
- DNA Methylation
- DNA Primers -- genetics
- DNA, Neoplasm -- chemistry
- Gene Deletion
- Gene Dosage
- Genes, APC
- Genes, Tumor Suppressor
- Heterozygote
- Humans
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Mice, Mutant Strains
- Models, Molecular
- Mutation
- Spectral Karyotyping
- Ubiquitin-Protein Ligases -- chemistry
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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