Next-generation sequencing of the TET2 gene in 355 MDS and CMML patients reveals low-abundance mutant clones with early origins, but indicates no definite prognostic value. [electronic resource]
Producer: 20101216Description: 3923-32 p. digitalISSN:- 1528-0020
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Amino Acid Substitution
- Base Sequence
- Cell Differentiation -- genetics
- DNA Mutational Analysis
- DNA-Binding Proteins -- genetics
- Dioxygenases
- Female
- Gene Expression
- Humans
- Janus Kinase 2 -- genetics
- Karyotyping
- Leukemia, Myelomonocytic, Chronic -- genetics
- Loss of Heterozygosity
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Myelodysplastic Syndromes -- genetics
- Polymorphism, Single Nucleotide
- Prognosis
- Proto-Oncogene Proteins -- genetics
- RNA, Messenger -- genetics
- RNA, Neoplasm -- genetics
- Survival Analysis
- T-Lymphocytes -- metabolism
- Young Adult
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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