The TRIB3 R84 variant is associated with increased carotid intima-media thickness in vivo and with enhanced MAPK signalling in human endothelial cells. [electronic resource]
Producer: 20110404Description: 184-92 p. digitalISSN:- 1755-3245
- Adult
- Aged
- Amino Acid Substitution
- Atherosclerosis -- genetics
- Carotid Artery, Common -- pathology
- Cell Adhesion -- genetics
- Cell Cycle Proteins -- genetics
- Cells, Cultured
- Endothelial Cells -- physiology
- Female
- Genetic Variation
- Humans
- Insulin Resistance -- genetics
- Intercellular Adhesion Molecule-1 -- metabolism
- MAP Kinase Signaling System -- genetics
- Male
- Middle Aged
- Monocytes -- physiology
- Nitric Oxide Synthase Type III -- metabolism
- Protein Serine-Threonine Kinases -- genetics
- Proto-Oncogene Proteins c-akt -- metabolism
- Repressor Proteins -- genetics
- Tunica Intima -- pathology
- Tunica Media -- pathology
- U937 Cells
- Vascular Cell Adhesion Molecule-1 -- metabolism
- Young Adult
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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