Epigenetic inactivation of the tumor suppressor gene RIZ1 in hepatocellular carcinoma involves both DNA methylation and histone modifications. [electronic resource]
Producer: 20110201Description: 889-95 p. digitalISSN:- 1600-0641
- Acetylation
- Azacitidine -- analogs & derivatives
- Carcinoma, Hepatocellular -- etiology
- Cell Line, Tumor
- DNA Methylation
- DNA-Binding Proteins -- antagonists & inhibitors
- Decitabine
- Epigenesis, Genetic
- Genes, Tumor Suppressor
- Histone-Lysine N-Methyltransferase -- antagonists & inhibitors
- Histones -- metabolism
- Humans
- Hydroxamic Acids -- pharmacology
- Liver Neoplasms -- etiology
- Nuclear Proteins -- antagonists & inhibitors
- Promoter Regions, Genetic
- RNA, Messenger -- analysis
- Transcription Factors -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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