Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation. [electronic resource]
Producer: 20101028Description: e11765 p. digitalISSN:- 1932-6203
- Blotting, Western
- Carrier Proteins -- genetics
- Caspase 1 -- metabolism
- Caspase Inhibitors
- Cathepsin B -- metabolism
- Cells, Cultured
- Cholesterol -- chemistry
- Chromatography, Thin Layer
- Cytochalasin D -- pharmacology
- Cytoplasm -- metabolism
- Humans
- Inflammation -- genetics
- Interleukin-1beta -- metabolism
- Lipopolysaccharides -- pharmacology
- Lysosomes -- drug effects
- Macrophages -- drug effects
- Microscopy, Confocal
- Monocytes -- drug effects
- NLR Family, Pyrin Domain-Containing 3 Protein
- Phagocytosis -- drug effects
- Potassium -- metabolism
- RNA, Small Interfering -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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