Potential in vivo amelioration by N-acetyl-L-cysteine of oxidative stress in brain in human double mutant APP/PS-1 knock-in mice: toward therapeutic modulation of mild cognitive impairment. [electronic resource]
Producer: 20110311Description: 2618-29 p. digitalISSN:- 1097-4547
- Acetylcysteine -- pharmacology
- Administration, Oral
- Alzheimer Disease -- drug therapy
- Amyloid beta-Protein Precursor -- genetics
- Animals
- Brain -- drug effects
- Cognition Disorders -- drug therapy
- Disease Models, Animal
- Drug Administration Schedule
- Gene Knock-In Techniques -- methods
- Humans
- Male
- Mice
- Mice, Transgenic
- Mutation -- genetics
- Oxidative Stress -- drug effects
- Presenilin-1 -- genetics
- Time Factors
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural
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