The Jak inhibitor CP-690,550 preserves the function of CD4CD25FoxP3 regulatory T cells and inhibits effector T cells. [electronic resource]
Producer: 20101115Description: 1785-95 p. digitalISSN:- 1600-6143
- CD4-Positive T-Lymphocytes -- drug effects
- Female
- Humans
- Interleukin-2 -- pharmacology
- Interleukin-2 Receptor alpha Subunit -- immunology
- Kidney Transplantation -- immunology
- Male
- Middle Aged
- Piperidines
- Pyrimidines -- pharmacology
- Pyrroles -- pharmacology
- STAT5 Transcription Factor -- antagonists & inhibitors
- T-Lymphocytes -- drug effects
- T-Lymphocytes, Regulatory -- drug effects
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Publication Type: Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't
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