Structures of native and affinity-enhanced WT1 epitopes bound to HLA-A*0201: implications for WT1-based cancer therapeutics. [electronic resource]
Producer: 20100914Description: 2519-24 p. digitalISSN:- 1872-9142
- Antigen Presentation
- Cancer Vaccines
- Crystallography, X-Ray
- Epitopes -- chemistry
- HLA-A Antigens -- chemistry
- HLA-A2 Antigen
- Humans
- Models, Molecular
- Neoplasms -- genetics
- Peptide Fragments -- chemistry
- Point Mutation
- Polymorphism, Single Nucleotide
- Protein Conformation
- Protein Engineering
- Protein Stability
- Static Electricity
- Structure-Activity Relationship
- WT1 Proteins -- chemistry
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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