The acyl-coenzyme A: cholesterol acyltransferase inhibitor CI-1011 reverses diffuse brain amyloid pathology in aged amyloid precursor protein transgenic mice. [electronic resource]
Producer: 20100827Description: 777-88 p. digitalISSN:- 1554-6578
- Acetamides
- Acetates -- pharmacology
- Aging -- drug effects
- Alzheimer Disease -- cerebrospinal fluid
- Amyloid -- metabolism
- Amyloid beta-Peptides -- metabolism
- Amyloid beta-Protein Precursor -- genetics
- Animals
- Apolipoproteins E -- metabolism
- Brain -- drug effects
- Cholesterol -- metabolism
- Disease Models, Animal
- Enzyme Inhibitors -- pharmacology
- Enzyme-Linked Immunosorbent Assay -- methods
- Gliosis -- drug therapy
- Humans
- Image Processing, Computer-Assisted
- Liver -- drug effects
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Mutation -- genetics
- Peptide Fragments -- metabolism
- Presenilin-1 -- metabolism
- Pyridines -- pharmacology
- Sterol O-Acyltransferase -- antagonists & inhibitors
- Sulfonamides
- Sulfonic Acids -- pharmacology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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