Enhanced susceptibility of HLA-mediated ticlopidine-induced idiosyncratic hepatotoxicity by CYP2B6 polymorphism in Japanese. [electronic resource]
Producer: 20101012Description: 298-306 p. digitalISSN:- 1880-0920
- Aryl Hydrocarbon Hydroxylases -- genetics
- Biotransformation -- genetics
- Case-Control Studies
- Chemical and Drug Induced Liver Injury -- epidemiology
- Cytochrome P-450 CYP2B6
- Enzyme Activation -- drug effects
- Genotype
- HLA Antigens -- genetics
- Haplotypes -- genetics
- Humans
- Japan -- epidemiology
- Oxidoreductases, N-Demethylating -- genetics
- Platelet Aggregation Inhibitors -- adverse effects
- Polymorphism, Single Nucleotide
- Ticlopidine -- adverse effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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