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  2. Details for: Spiroindane based amides as potent and selective MC4R agonists for the treatment of obesity.
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Spiroindane based amides as potent and selective MC4R agonists for the treatment of obesity. [electronic resource]

By:
  • He, Shuwen
Contributor(s):
  • Ye, Zhixiong
  • Dobbelaar, Peter H
  • Sebhat, Iyassu K
  • Guo, Liangqin
  • Liu, Jian
  • Jian, Tianying
  • Lai, Yingjie
  • Franklin, Christopher L
  • Bakshi, Raman K
  • Dellureficio, James P
  • Hong, Qingmei
  • Weinberg, David H
  • Macneil, Tanya
  • Tang, Rui
  • Strack, Alison M
  • Tamvakopoulos, Constantin
  • Peng, Qianping
  • Miller, Randy R
  • Stearns, Ralph A
  • Chen, Howard Y
  • Chen, Airu S
  • Fong, Tung M
  • Wyvratt, Matthew J
  • Nargund, Ravi P
Producer: 20101123Description: 4399-405 p. digitalISSN:
  • 1464-3405
Subject(s):
  • Amides -- chemistry
  • Animals
  • Anti-Obesity Agents -- chemistry
  • Body Weight -- drug effects
  • Humans
  • Mice
  • Mice, Knockout
  • Obesity -- drug therapy
  • Pyrrolidines -- chemistry
  • Rats
  • Rats, Sprague-Dawley
  • Receptor, Melanocortin, Type 4 -- agonists
  • Spiro Compounds -- chemistry
  • Structure-Activity Relationship
Online resources:
  • Available from publisher's website
In: Bioorganic & medicinal chemistry letters vol. 20
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Publication Type: Journal Article

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Spiroindane based amides as potent and selective MC4R agonists for the treatment of obesity.

APA

He S., Ye Z., Dobbelaar P. H., Sebhat I. K., Guo L., Liu J., Jian T., Lai Y., Franklin C. L., Bakshi R. K., Dellureficio J. P., Hong Q., Weinberg D. H., Macneil T., Tang R., Strack A. M., Tamvakopoulos C., Peng Q., Miller R. R., Stearns R. A., Chen H. Y., Chen A. S., Fong T. M., Wyvratt M. J. & Nargund R. P. (20101123). Spiroindane based amides as potent and selective MC4R agonists for the treatment of obesity. : Bioorganic & medicinal chemistry letters.

Chicago

He Shuwen, Ye Zhixiong, Dobbelaar Peter H, Sebhat Iyassu K, Guo Liangqin, Liu Jian, Jian Tianying, Lai Yingjie, Franklin Christopher L, Bakshi Raman K, Dellureficio James P, Hong Qingmei, Weinberg David H, Macneil Tanya, Tang Rui, Strack Alison M, Tamvakopoulos Constantin, Peng Qianping, Miller Randy R, Stearns Ralph A, Chen Howard Y, Chen Airu S, Fong Tung M, Wyvratt Matthew J and Nargund Ravi P. 20101123. Spiroindane based amides as potent and selective MC4R agonists for the treatment of obesity. : Bioorganic & medicinal chemistry letters.

Harvard

He S., Ye Z., Dobbelaar P. H., Sebhat I. K., Guo L., Liu J., Jian T., Lai Y., Franklin C. L., Bakshi R. K., Dellureficio J. P., Hong Q., Weinberg D. H., Macneil T., Tang R., Strack A. M., Tamvakopoulos C., Peng Q., Miller R. R., Stearns R. A., Chen H. Y., Chen A. S., Fong T. M., Wyvratt M. J. and Nargund R. P. (20101123). Spiroindane based amides as potent and selective MC4R agonists for the treatment of obesity. : Bioorganic & medicinal chemistry letters.

MLA

He Shuwen, Ye Zhixiong, Dobbelaar Peter H, Sebhat Iyassu K, Guo Liangqin, Liu Jian, Jian Tianying, Lai Yingjie, Franklin Christopher L, Bakshi Raman K, Dellureficio James P, Hong Qingmei, Weinberg David H, Macneil Tanya, Tang Rui, Strack Alison M, Tamvakopoulos Constantin, Peng Qianping, Miller Randy R, Stearns Ralph A, Chen Howard Y, Chen Airu S, Fong Tung M, Wyvratt Matthew J and Nargund Ravi P. Spiroindane based amides as potent and selective MC4R agonists for the treatment of obesity. : Bioorganic & medicinal chemistry letters. 20101123.

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