Knockdown of Clock in the ventral tegmental area through RNA interference results in a mixed state of mania and depression-like behavior. [electronic resource]
Producer: 20110120Description: 503-11 p. digitalISSN:- 1873-2402
- Action Potentials -- physiology
- Animals
- Animals, Genetically Modified
- Anxiety -- genetics
- Bipolar Disorder -- genetics
- CLOCK Proteins -- genetics
- Circadian Rhythm -- genetics
- Dependovirus -- genetics
- Depression -- genetics
- Dopamine -- metabolism
- Gene Expression
- Gene Knockdown Techniques -- methods
- Gene Transfer Techniques
- Genetic Vectors
- Male
- Mice
- Mice, Inbred C57BL -- genetics
- Neurons -- physiology
- RNA Interference
- Ventral Tegmental Area -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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