Nutlin-3, the small-molecule inhibitor of MDM2, promotes senescence and radiosensitises laryngeal carcinoma cells harbouring wild-type p53. [electronic resource]
Producer: 20100805Description: 186-95 p. digitalISSN:- 1532-1827
- Animals
- Carcinoma, Squamous Cell -- drug therapy
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Cellular Senescence -- drug effects
- Genes, p53
- Imidazoles -- analysis
- Laryngeal Neoplasms -- drug therapy
- Piperazines -- analysis
- Proto-Oncogene Proteins c-mdm2 -- antagonists & inhibitors
- Radiation Tolerance -- drug effects
- Radiation-Sensitizing Agents -- pharmacology
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Publication Type: Journal Article
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