Are osteoclasts needed for the bone anabolic response to parathyroid hormone? A study of intermittent parathyroid hormone with denosumab or alendronate in knock-in mice expressing humanized RANKL. [electronic resource]
Producer: 20101005Description: 28164-73 p. digitalISSN:- 1083-351X
- Alendronate -- administration & dosage
- Animals
- Antibodies, Monoclonal -- administration & dosage
- Antibodies, Monoclonal, Humanized
- Biomarkers -- metabolism
- Bone Density -- drug effects
- Bone Resorption -- drug therapy
- Bone and Bones -- cytology
- Denosumab
- Dose-Response Relationship, Drug
- Female
- Gene Expression
- Gene Knock-In Techniques
- Humans
- Male
- Mice
- Osteoclasts -- drug effects
- Osteogenesis -- drug effects
- Ovariectomy
- Parathyroid Hormone -- administration & dosage
- RANK Ligand -- administration & dosage
- Receptor Activator of Nuclear Factor-kappa B -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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