Pharmacokinetics and toxicodynamics of oxaliplatin in rats: application of a toxicity factor to explain differences in the nephrotoxicity and myelosuppression induced by oxaliplatin and the other platinum antitumor derivatives. [electronic resource]
Producer: 20101221Description: 1893-9 p. digitalISSN:- 1573-904X
- Animals
- Antineoplastic Agents -- pharmacokinetics
- Area Under Curve
- Blood Urea Nitrogen
- Bone Marrow -- drug effects
- Dose-Response Relationship, Drug
- Drug Stability
- Hydrolysis
- Infusions, Intravenous
- Injections, Intravenous
- Kidney -- drug effects
- Male
- Metabolic Clearance Rate
- Models, Biological
- Molecular Structure
- Organoplatinum Compounds -- pharmacokinetics
- Oxaliplatin
- Platelet Count
- Rats
- Rats, Wistar
- Time Factors
- Tissue Distribution
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Publication Type: Journal Article
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