Poly(ADP-ribose) polymerase is hyperactivated in homologous recombination-defective cells. [electronic resource]
Producer: 20100809Description: 5389-98 p. digitalISSN:- 1538-7445
- Animals
- Cell Line, Tumor
- Cricetinae
- DNA Damage
- DNA Replication
- DNA, Neoplasm -- genetics
- Enzyme Activation
- Gene Knockout Techniques
- Genes, BRCA1
- Genes, BRCA2
- Humans
- Mutation
- Neoplasms -- enzymology
- Poly (ADP-Ribose) Polymerase-1
- Poly(ADP-ribose) Polymerase Inhibitors
- Poly(ADP-ribose) Polymerases -- metabolism
- Recombination, Genetic
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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