Structure of the human mTOR complex I and its implications for rapamycin inhibition. [electronic resource]
Producer: 20100629Description: 768-74 p. digitalISSN:- 1097-4164
- Adaptor Proteins, Signal Transducing
- Antibiotics, Antineoplastic -- chemistry
- Cell Line
- Computer Simulation
- Cryoelectron Microscopy
- Humans
- Mechanistic Target of Rapamycin Complex 1
- Models, Molecular
- Multiprotein Complexes
- Protein Multimerization
- Protein Structure, Quaternary
- Protein Structure, Tertiary
- Protein Subunits -- chemistry
- Proteins -- chemistry
- Regulatory-Associated Protein of mTOR
- Sirolimus -- chemistry
- TOR Serine-Threonine Kinases
- Tacrolimus Binding Protein 1A -- chemistry
- Transcription Factors -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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