Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. [electronic resource]
Producer: 20100722Description: 808-12 p. digitalISSN:- 1476-4687
- Adult
- Cell Differentiation
- Cell Line
- Cell Lineage
- Cells, Cultured
- Embryonic Stem Cells -- metabolism
- Enzyme Activation
- Female
- Fibroblasts -- metabolism
- Gene Expression Profiling
- Homeodomain Proteins -- genetics
- Humans
- Induced Pluripotent Stem Cells -- enzymology
- LEOPARD Syndrome -- drug therapy
- Male
- Mitogen-Activated Protein Kinases -- metabolism
- Models, Biological
- Myocytes, Cardiac -- metabolism
- NFATC Transcription Factors -- genetics
- Nanog Homeobox Protein
- Octamer Transcription Factor-3 -- genetics
- Phosphoproteins -- analysis
- Polymerase Chain Reaction
- Precision Medicine
- Protein Tyrosine Phosphatase, Non-Receptor Type 11 -- genetics
- SOXB1 Transcription Factors -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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