Dexamethasone destabilizes Nmyc to inhibit the growth of hedgehog-associated medulloblastoma. [electronic resource]
Producer: 20100809Description: 5220-5 p. digitalISSN:- 1538-7445
- Animals
- Brain Neoplasms -- drug therapy
- Dexamethasone -- pharmacology
- Glycogen Synthase Kinase 3 -- metabolism
- Glycogen Synthase Kinase 3 beta
- Hedgehog Proteins -- antagonists & inhibitors
- Medulloblastoma -- drug therapy
- Mice
- Mice, Transgenic
- Phosphorylation
- Protein Structure, Tertiary
- Proto-Oncogene Proteins c-myc -- antagonists & inhibitors
- Signal Transduction
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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