Complement activation mediates cetuximab inhibition of non-small cell lung cancer tumor growth in vivo. [electronic resource]
Producer: 20100730Description: 139 p. digitalISSN:- 1476-4598
- Animals
- Antibodies, Monoclonal -- pharmacology
- Antibodies, Monoclonal, Humanized
- Antineoplastic Agents -- pharmacology
- Carcinoma, Non-Small-Cell Lung -- drug therapy
- Cell Line, Tumor
- Cetuximab
- Complement Activation -- drug effects
- ErbB Receptors -- biosynthesis
- Female
- Fluorescent Antibody Technique
- Humans
- Lung Neoplasms -- drug therapy
- Mice
- Mice, Nude
- Mutation
- Polymerase Chain Reaction
- Proto-Oncogene Proteins -- genetics
- Proto-Oncogene Proteins p21(ras)
- RNA, Messenger -- analysis
- Xenograft Model Antitumor Assays
- ras Proteins -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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