Embryonic stem cell (ESC)-mediated transgene delivery induces growth suppression, apoptosis and radiosensitization, and overcomes temozolomide resistance in malignant gliomas. [electronic resource]
Producer: 20101130Description: 664-74 p. digitalISSN:- 1476-5500
- Animals
- Antineoplastic Agents, Alkylating -- therapeutic use
- Apoptosis
- Blotting, Western
- Brain Neoplasms -- drug therapy
- Cell Proliferation
- Cells, Cultured
- Combined Modality Therapy
- Dacarbazine -- analogs & derivatives
- Drug Delivery Systems
- Drug Resistance, Neoplasm -- genetics
- Embryonic Stem Cells -- physiology
- Enzyme-Linked Immunosorbent Assay
- Female
- Gene Transfer Techniques
- Genetic Therapy
- Genetic Vectors -- therapeutic use
- Glioma -- drug therapy
- Humans
- Immunoenzyme Techniques
- Interleukins -- genetics
- Mice
- Mice, Nude
- RNA, Messenger -- genetics
- Radiation, Ionizing
- Radiation-Sensitizing Agents
- Reverse Transcriptase Polymerase Chain Reaction
- Temozolomide
- Transgenes -- physiology
- Tumor Stem Cell Assay
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural
There are no comments on this title.
Log in to your account to post a comment.