Gfi1 expression is controlled by five distinct regulatory regions spread over 100 kilobases, with Scl/Tal1, Gata2, PU.1, Erg, Meis1, and Runx1 acting as upstream regulators in early hematopoietic cells. [electronic resource]
Producer: 20100806Description: 3853-63 p. digitalISSN:- 1098-5549
- Animals
- Basic Helix-Loop-Helix Transcription Factors
- Cell Differentiation -- genetics
- Cell Line
- Chromatin Immunoprecipitation
- Hematopoiesis -- genetics
- Hematopoietic Stem Cells -- cytology
- Hematopoietic System -- metabolism
- Homeodomain Proteins
- Intercellular Signaling Peptides and Proteins -- genetics
- Mice
- Mice, Transgenic
- Myeloid Ecotropic Viral Integration Site 1 Protein
- Neoplasm Proteins
- Proto-Oncogene Proteins
- Regulatory Sequences, Nucleic Acid
- T-Cell Acute Lymphocytic Leukemia Protein 1
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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