Suppression of growth arrest and DNA damage-inducible 45alpha expression confers resistance to sulindac and indomethacin-induced gastric mucosal injury. [electronic resource]
Producer: 20100923Description: 693-702 p. digitalISSN:- 1521-0103
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- toxicity
- Antisense Elements (Genetics) -- pharmacology
- Apoptosis -- drug effects
- Caspase 9 -- metabolism
- Caspase Inhibitors
- Cell Cycle Proteins -- antagonists & inhibitors
- Cell Proliferation -- drug effects
- Cyclooxygenase 1 -- metabolism
- Cyclooxygenase 2 Inhibitors -- pharmacology
- Cyclooxygenase Inhibitors -- pharmacology
- DNA Damage
- Dinoprostone -- pharmacology
- Endothelial Cells -- drug effects
- Enzyme Activation -- drug effects
- Gastric Mucosa -- pathology
- Humans
- Indomethacin -- toxicity
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Nuclear Proteins -- antagonists & inhibitors
- RNA, Small Interfering -- pharmacology
- Rats
- Reverse Transcriptase Polymerase Chain Reaction
- Stomach Ulcer -- chemically induced
- Sulindac -- toxicity
- Up-Regulation
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
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