The resistance mutation R155K in the NS3/4A protease of hepatitis C virus also leads the virus to escape from HLA-A*68-restricted CD8 T cells. [electronic resource]
Producer: 20101019Description: 272-5 p. digitalISSN:- 1872-9096
- Amino Acid Substitution -- genetics
- Antiviral Agents -- pharmacology
- CD8-Positive T-Lymphocytes -- immunology
- Carbamates -- pharmacology
- Carrier Proteins -- genetics
- Drug Resistance, Viral
- Epitopes, T-Lymphocyte -- genetics
- HLA-A Antigens -- immunology
- Hepacivirus -- growth & development
- Humans
- Intracellular Signaling Peptides and Proteins
- Macrocyclic Compounds -- pharmacology
- Mutation, Missense
- Quinolines -- pharmacology
- Thiazoles -- pharmacology
- Viral Nonstructural Proteins -- genetics
- Viral Proteins -- genetics
- Virus Replication
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Publication Type: Journal Article
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