HT1080/DR4: a P-glycoprotein-negative human fibrosarcoma cell line exhibiting resistance to topoisomerase II-reactive drugs despite the presence of a drug-sensitive topoisomerase II. [electronic resource]
Producer: 19901023Description: 1553-61 p. digitalISSN:- 0027-8874
- ATP Binding Cassette Transporter, Subfamily B, Member 1
- Amsacrine -- pharmacology
- Catalase -- metabolism
- Cell Line
- Cell Nucleus -- metabolism
- DNA Probes
- DNA Topoisomerases, Type II -- isolation & purification
- Doxorubicin -- pharmacology
- Drug Resistance -- genetics
- Etoposide -- pharmacology
- Fibrosarcoma
- Glucosephosphate Dehydrogenase -- metabolism
- Glutathione Peroxidase -- metabolism
- Glutathione Reductase -- metabolism
- Glutathione Transferase -- metabolism
- Humans
- Kinetics
- Membrane Glycoproteins -- analysis
- Neoplasm Proteins -- analysis
- Superoxide Dismutase -- metabolism
- Topoisomerase II Inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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