7-Ketocholesterol and cholesterol-5alpha,6alpha-epoxide induce smooth muscle cell migration and proliferation through the epidermal growth factor receptor/phosphoinositide 3-kinase/Akt signaling pathways. [electronic resource]
Producer: 20100727Description: 88-96 p. digitalISSN:- 1879-3169
- Animals
- Aorta
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Ceramides -- metabolism
- Cholesterol -- analogs & derivatives
- ErbB Receptors -- metabolism
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Intracellular Signaling Peptides and Proteins -- metabolism
- Ketocholesterols -- toxicity
- Matrix Metalloproteinase 2 -- metabolism
- Matrix Metalloproteinase 9 -- metabolism
- Muscle, Smooth, Vascular -- cytology
- Myocytes, Smooth Muscle -- cytology
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphorylation
- Protein Serine-Threonine Kinases -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- RNA, Messenger -- genetics
- Rats
- Signal Transduction -- drug effects
- Sphingomyelins -- metabolism
- TOR Serine-Threonine Kinases
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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