Beat-by-beat QT interval variability, but not QT prolongation per se, predicts drug-induced torsades de pointes in the anaesthetised methoxamine-sensitized rabbit. [electronic resource]
Producer: 20110801Description: 40-6 p. digitalISSN:- 1873-488X
- Animals
- Anti-Arrhythmia Agents -- pharmacology
- Arrhythmias, Cardiac -- chemically induced
- Cell Line
- ERG1 Potassium Channel
- Electrocardiography
- Embryo, Mammalian
- Ether-A-Go-Go Potassium Channels -- metabolism
- Heart -- drug effects
- Humans
- Ion Channels -- antagonists & inhibitors
- Kidney
- Long QT Syndrome -- chemically induced
- Male
- Methoxamine -- pharmacology
- Models, Statistical
- Phenethylamines -- pharmacology
- Rabbits
- Rats
- Sulfonamides -- pharmacology
- Torsades de Pointes -- chemically induced
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Publication Type: Journal Article
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