Kidney-specific inactivation of Ofd1 leads to renal cystic disease associated with upregulation of the mTOR pathway. [electronic resource]
Producer: 20100928Description: 2792-803 p. digitalISSN:- 1460-2083
- Animals
- Cells, Cultured
- Cilia -- genetics
- Disease Progression
- Dogs
- Epithelial Cells -- metabolism
- Female
- Gene Silencing -- physiology
- Intracellular Signaling Peptides and Proteins -- genetics
- Kidney -- metabolism
- Kidney Diseases, Cystic -- genetics
- Male
- Mice
- Mice, Transgenic
- Organ Specificity -- genetics
- Protein Serine-Threonine Kinases -- genetics
- Proteins -- antagonists & inhibitors
- Signal Transduction -- physiology
- TOR Serine-Threonine Kinases
- Up-Regulation
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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