Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A synthase by antibiotic 1233A and other beta-lactones. [electronic resource]
Producer: 19900726Description: 610-6 p. digitalISSN:- 0006-291X
- Acetates -- metabolism
- Animals
- Anti-Bacterial Agents -- pharmacology
- Carcinoma, Hepatocellular
- Cell Line
- Cholestyramine Resin -- pharmacology
- Fatty Acids, Unsaturated -- pharmacology
- Humans
- Hydroxymethylglutaryl-CoA Synthase -- antagonists & inhibitors
- Kinetics
- Lactones -- pharmacology
- Liver -- drug effects
- Liver Neoplasms
- Lovastatin -- pharmacology
- Molecular Structure
- Oxo-Acid-Lyases -- antagonists & inhibitors
- Rats
- Structure-Activity Relationship
- Tumor Cells, Cultured -- drug effects
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Publication Type: Journal Article
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